THCV - The Lesser-Known Cannabinoid
Health

THCV – The Lesser-Known Cannabinoid With Potential Health Benefits

June 22, 2023

As researchers continue to explore this little cannabinoid, it’s becoming clear that THCV is quite the powerhouse. It has various therapeutic properties, including being an anti-psychotic, appetite suppressant, and regulating blood sugar levels.

At low doses, THCV interacts with the CB1 receptors in the endocannabinoid system to reduce its psychoactive effects and produce softer symptoms like anxiolysis and hypothermia. It also enhances insulin sensitivity and decreases food reward and desire, making it an effective treatment for obesity and diabetes.

It’s Non-Psychoactive

What is THCV? THCV is known to have some very distinct characteristics, making it unique among the cannabinoid family. Most of the research is on animals, but early signs are promising that THCV may be able to suppress appetite, reduce blood sugar levels and stimulate bone growth.

A THCV-induced reduction in appetite is believed to be due to its ability to block the CB1 receptor, which stimulates hunger. Animal studies also show that THCV significantly reduces glucose levels in the blood and improves insulin sensitivity.

Unlike THC, THCV does not affect the mental state and therefore does not produce psychoactive effects. Instead, THCV is known to cause a mellow high that can be relaxing and even social. Moreover, it is a neuroprotective cannabinoid that may help reduce the tremors and impaired motor control associated with Alzheimer’s disease. Similarly, THCV has been shown to alleviate nausea in patients with gastrointestinal disorders. Moreover, it is also a natural bone stimulator that encourages new bone-cell formation and reduces osteoporosis symptoms.

It’s Non-Intoxicating

THCV is known for promoting bone growth and strengthening the immune system. It’s also an anti-inflammatory, analgesic, anti-nausea, and anxiety reducer. This cannabinoid also binds to CB receptors in the skeletal endocannabinoid system (SES), and research shows that it stimulates the growth of new bone cells and slows or prevents bone degeneration.

Unlike THC, known to cause munchies, THCV has been shown in animal research to induce hypophagia (a decreased appetite). This could help people with diabetes regulate their blood sugar levels and those who struggle with obesity and overweight issues.

In addition, THCV has been shown to reduce the effects of THC, such as increased heart rate and a subjective feeling of intoxication. As more cannabis cultivators harvest THCV-rich strains, we’ll see advanced manufactured products infused with this cannabinoid, like edibles and vape juice. This opens up the possibility of rising yields and supply chain access for this lesser-known cannabinoid.

It’s A Non-Stimulating Cannabinoid

THCV is a natural appetite suppressant that stimulates insulin production, which helps control blood sugar levels. Research also shows it can inhibit the breakdown of glucose and reduce blood lipids, making THCV an excellent choice for anyone trying to lose weight or fight against diabetes.

Unlike THC, THCV does not produce a psychoactive effect in low doses. Instead, it has a clearer mind and focuses the attention on the task at hand. Users report that THCV allows them to be fully aware of their surroundings, and many prefer this to the “high” THC produces.

THCV is also neuroprotective, protecting the nervous system from damage. In addition, it acts as an anti-nauseant and can help with digestive issues. It also promotes bone growth by binding to CB receptors in the skeletal system, which may slow or prevent osteoporosis.

It’s A Non-Stimulating Endocannabinoid

THC and THCV differ because THC acts as an agonist at the CB1 receptors, while THCV exhibits antagonistic activity. This means that it blocks the effects of THC, which can make you feel anxious or nervous. THCV may also reduce some of the psychoactive effects of THC, such as paranoia and hallucinations.

In addition to inhibiting THC’s psychoactive effects, THCV stimulates bone growth and encourages a healthy metabolic system. It is being looked at as a treatment for osteoporosis and other bone-related diseases.

Several studies have found that THCV reduces glucose intolerance and increases insulin sensitivity in mice. THCV also acts as an anti-obesity agent, although it is unknown exactly how. One theory is that it competes with endogenous endocannabinoids for the CB1 receptor, suppressing their activity and preventing the “munchies.” Other studies have shown that THCV reduces food intake in obese mice. Additionally, THCV may decrease hepatocyte lipid accumulation and improve mouse pancreatic b-cell function.

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